Current Projects

Synaptic Connectivity Motifs of Horizontal Cell Dendrites in the Tree Shrew Superficial Superior Colliculus: A 3D EM Connectomics Study

Francesca Sciaccotta, Stephanie Zhang, Rebecca Roberts, and Alev Erisir
 

Double Hoo 2024: Stephanie Zhang and Francesca Sciaccotta

 

 

 Synaptic Circuitry of Koniocellular vs. Magno / Parvo Pathways in the Tree Shrew Visual Thalamus

 

Characterization of Axon Terminals from Superior Colliculus in the Tree Shrew LGN. (Lead: Francesca Sciaccotta)

Morphological Properties of Magno/Parvo and Koniocellular Retinal Ganglion Cell Axons in the Tree Shrew LGN.  (Lead: Sciaccotta)  

 

EM Connectomics Studies of the Visual Pathways  

 

Selectivity of Synaptic Inputs in Developing Mouse LGN. (Lead: Sydney Horton)

Selectivity of Synaptic Inputs onto Dendrite Segments in the Mouse Visual Thalamus, using 3D EM connectomics and modeling. Maher,  Briegel, Imtiaz, Fox, Golino, Erisir, 2023Frontiers Neuroanatomy.

 

Ultrastructural Neuropathology

Oligodendrocyte Hypermotility is the Earliest Culprit of Neuropil Damage and Degeneration in a Transgenic Mouse Model of Alzheimer's Disease: An Electron Microscopy Study 
  
Alev Erisir, Zoe Anderson, Kerem Birisik, Sahil Chawla, Lauren Hanley, Erin Maher, Ezgi S. Toklucu and Elif Keskinoz 

Progression of Cellular Damage in Basal Forebrain

Ependymal Cell alterations in the 3xTg mice 

Have you seen an amyloid plaque so up close?

Mitochondrial Alterations in Alzheimer's Disease: Insight from the 5xFAD Mouse Model. Elif Nedret Keskinoz, Musa Celik, Ezgi Sila Toklucu, Kerem Birisik, Alev Erisir, Devrim Oz Arslan.

Ezgi Toklucu and Kerem Birisik have been visiting scholars in the lab through Summer 2024. 

 

Mechanisms of Oxytocin Release in Prairie Vole Brain

 

The Histochemical Brain Atlas of The Prairie Vole (Microtus ochrogaster). 2024  Erin Ramos, Griffin Jiron Zoe Anderson, and Alev Erisir


The central oxytocinergic system of the prairie vole.
Ramos EN, Jiron GM, Danoff JS, Anderson Z, Carter CS, Perkeybile AM, Connelly JJ, Erisir A.
Brain Struct Funct. 2024 Jul 23.  

Congratulations to Erin Ramos, PhD