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    The overall goal of our research is to study the neural basis of vision: how neurons in the brain respond to visual stimuli; what neural circuits give rise to such response properties; and how these circuits are established during development. We use mice and tree shrews as models and take an integrative approach that combines in vivo physiology, two-photon imaging, genetics, behavioral, and computational techniques. Our research is mainly along two directions. 

    1. We made a paradigm-shifting discovery regarding how sensory experience shapes visual functions in the cortex during a critical period in early life. 

    2. We have carried out a series of functional studies of the mouse superior colliculus, helping to establish it as a new model for studying visual information processing and sensorimotor transformation. 

     

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Recent Publications

  • Development and binocular matching of orientation selectivity in visual cortex: a computational model.
  • Effects of Locomotion on Visual Responses in the Mouse Superior Colliculus
  • Visual Function, Organization, and Development of the Mouse Superior Colliculus.
  • Bidirectional encoding of motion contrast in the mouse superior colliculus.
  • Transformation of Feature Selectivity From Membrane Potential to Spikes in the Mouse Superior Colliculus.
  • Environmental enrichment rescues binocular matching of orientation preference in the mouse visual cortex
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Contact

Jianhua Cang
Email: cang@virginia.edu
Lab Phone: (434) 924-1116
Office Phone: (434) 924-1117

 

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