The overall goal of our research is to study the neural basis of vision: how neurons in the brain respond to visual stimuli; what neural circuits give rise to such response properties; and how these circuits are established during development. We use mice as a model and take an integrative approach that combines in vivo physiology, two-photon imaging, genetics, behavioral, and computational techniques. Our research is mainly along two directions. 

1. We made a paradigm-shifting discovery regarding how sensory experience shapes visual functions in the cortex during a critical period in early life. 

2. We have carried out a series of functional studies of the mouse superior colliculus, helping to establish it as a new model for studying visual information processing and sensorimotor transformation. 

We are now continuing both lines of research in mice by performing mechanistic studies of critical period plasticity in the cortex and visual transformation and development in the superior colliculus.... Read more about About