Sleep and circadian disruptions often precede the onset of memory problems in AD. We are interested to learn whether strengthening the sleep/wake cycle or circadian rhythmicity slows the progression of AD. With the support from Alzheimer's Association, we will develop a timed exercise, meal and light regiment that increases circadian rhythmicity in mice. We will then determine whether this treatment improves pathology and memory in an AD mouse model. 

In the news:

Alzheimer’s Association grant allows UVA professor to take on new sleep study

Feel Good Friday: Grant for Alzheimer's research project